The file contains correspondence illustrating interactions between the Great Northern Railroad and the Indian reservations. The materials include letters and telegraphs involving the Office of Indian Affairs, the Department of the Interior, and the United States Indian Service. The documents are photocopies.

A few of the letters reference Sitting Bull and Bloody Mouth. Several letters concern illegal trade. There are also brief reports regarding the Indian Schools. The 1905 report lists the salaries at the Indian School, and the 1907 report notes inconsistencies in religious education. Papers are photostats of miscellaneous handwritten correspondence.